Physical fitness and lifetime cognitive change
Physical fitness and lifetime cognitive change
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DOI：
10.1212/01.wnl.0000238520.06958.6a
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发表时间：
2006-10-10
期刊：
影响因子：
9.9
通讯作者：
Starr, John M.
中科院分区：
文献类型：
--
作者：
Deary, Ian J.;Whalley, Lawrence J.;Starr, John M.
目的：检验身体健康与更成功的认知老化相关的假设。方法：1932 年苏格兰心理调查的幸存参与者 (N = 460) 在 11 岁和 79 岁时接受了相同的一般认知测试。在 79 岁时评估握力、6 米步行时间和肺功能（1 秒内用力呼气量 [FEV1]）。结果：通过对三种健身指标的主成分分析得出的潜在身体健身特征与成功的认知老化显着相关。 11 岁时的认知评分、性别、社会阶层和 APOE-epsilon 4 基因型均作为协变量包含在内。儿童时期较高的智商与老年时较好的肺功能有关。结论：身体健康与认知储备相关。旨在让老年人更健康的干预研究是改善认知老化的良好候选者。
Objective: To test the hypothesis that physical fitness is associated with more successful cognitive aging. Methods: Surviving participants (N = 460) of the Scottish Mental Survey of 1932 were tested on the same general cognitive test at age 11 and 79 years. Measures of grip strength, 6-meter walk time, and lung function (forced expiratory volume from the lungs in 1 second [FEV1]) were assessed at age 79 years. Results: A latent physical fitness trait, derived by principal components analysis of the three fitness measures, was significantly associated with successful cognitive aging. Cognitive score at age 11, sex, social class, and APOE-epsilon 4 genotype were included as covariables. Higher childhood IQ was associated with better lung function in old age. Conclusions: Physical fitness is associated with cognitive reserve. Intervention studies aimed at making older people fitter are good candidates to improve cognitive aging.