Treatment of Facial Lentigines in Peutz–Jeghers Syndrome With an Intense Pulsed Light Source
Treatment of Facial Lentigines in Peutz–Jeghers Syndrome With an Intense Pulsed Light Source
复制标题
用强脉冲光源治疗黑斑息肉综合征的面部雀斑
作者：
B. Remington;T. Remington
Peutz-Jeghers综合征是一种遗传性疾病，其特征是独特的粘膜皮肤雀斑样痣和肠错构瘤性息肉病。皮肤病变可能会导致美容毁容，并且经常带来治疗挑战。目的：确定强脉冲光（IPL）治疗Peutz-Jeghers综合征面部雀斑样痣是否有效。方法强脉冲光，利用590 nm的截止滤波器，用于治疗一个10岁的女孩与Peutz-Jeghers综合征的面部雀斑。在12个疗程中，每个疗程针对不同的面部区域，治疗区域的雀斑被完全清除。大多数的雀斑在一次治疗后就消退了，少数区域需要第二次治疗。结论在本例中，强脉冲光治疗可显著改善美容性毁容性雀斑。据我们所知，这是首次报告使用强脉冲光在Peutz-Jeghers综合征。
BACKGROUNDPeutz–Jeghers syndrome is a hereditary condition characterized by distinctive mucocutaneous lentigines and intestinal hamartomatous polyposis. The cutaneous lesions may be cosmetically disfiguring and frequently present a therapeutic challenge. OBJECTIVETo determine if intense pulsed light (IPL) is effective in treating facial lentigines in Peutz–Jeghers syndrome. METHODSThe IPL, utilizing a 590 nm cutoff filter, was used to treat facial lentigines in a 10-year-old girl with Peutz–Jeghers syndrome. RESULTSA series of 12 treatment sessions, each to different facial regions, resulted in complete clearance of lentigines in the treated areas. Most of the lentigines resolved after a single treatment, with a few areas requiring a second treatment. CONCLUSIONIn this case, treatment with IPL resulted in dramatic improvement of cosmetically disfiguring lentigines. To our knowledge, this is the first report of using IPL in Peutz–Jeghers syndrome.