Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines:: Application in the construction of the communesin ring system
Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines:: Application in the construction of the communesin ring system
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DOI：
10.1021/ol061461d
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发表时间：
2006-08-31
期刊：
影响因子：
5.2
通讯作者：
Funk, Raymond L.
中科院分区：
文献类型：
--
作者：
Crawley, Seth L.;Funk, Raymond L.
描述了一种通过酸催化或氟化物促进 2-(2-酰氨基苯基)氮丙啶开环生成氮杂邻二甲苯的新方案。该方法已被用于快速构建 communesin B 的六环子结构。
A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl) aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.