Association between arterial inflow and venous outflow in idiopathic and secondary intracranial hypertension
Association between arterial inflow and venous outflow in idiopathic and secondary intracranial hypertension
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DOI：
10.1016/j.jocn.2005.06.005
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发表时间：
2006-06-01
影响因子：
2
通讯作者：
Bateman, Grant A.
中科院分区：
文献类型：
--
作者：
Bateman, Grant A.
24例临床诊断为特发性颅内高压的患者接受了标准磁共振（MR）成像。根据MR静脉造影，可以确定两组患者：（i）一组为内源性静脉流出道阻塞（内源性）;（ii）一组为非内源性阻塞（外源性）。进行脑动脉和静脉的MRI流量定量研究，测量动脉血流入以及上级矢状窦（SSS）和直窦（ST）流出。MR静脉造影证实12例为内源性，12例为外源性。在内源性组中，总动脉流入量正常;然而，SSS流出量减少了35%（p = 0.0001）。外源性患者的动脉流入量比正常值高55%（p = 0.0001）;然而，SSS血流正常。在内源性静脉流出道阻塞中，尽管流出道减少，但总脑流入量仍保持不变。在，特发性。例出现脑充血，提示脑血管自动调节功能紊乱。皇冠版权所有（C）2006年出版的爱思唯尔有限公司保留所有权利。
Twenty-four patients with a clinical diagnosis of idiopathic intracranial hypertension underwent standard magnetic resonance (MR) imaging. On the basis of MR venography, two groups of patients could be identified: (i) one group with an intrinsic venous outflow obstruction (intrinsic); and (ii) a non-intrinsically obstructed (extrinsic) group. MRI flow quantification studies of the cerebral arteries and veins, measuring arterial blood inflow as well as superior sagittal sinus (SSS) and straight sinus (ST) outflow, were performed. The MR venography confirmed that there were 12 intrinsic patients and 12 extrinsic patients. In the intrinsic group, total arterial inflow was normal; however, the SSS outflow was reduced by 35% (p = 0.0001). Arterial inflow in extrinsic patients was 55% higher than normal (p = 0.0001); however, the SSS flow was normal. In intrinsic venous outflow obstruction, total cerebral inflow is maintained despite a reduction in outflow. In,the idiopathic. cases, there was cerebral hyperaemia suggesting a derangement of autoregulation. Crown Copyright (C) 2006 Published by Elsevier Ltd. All rights reserved.