Patient-specific computational fluid dynamics: structured mesh generation from coronary angiography
Patient-specific computational fluid dynamics: structured mesh generation from coronary angiography
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DOI：
10.1007/s11517-010-0583-4
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发表时间：
2010-04-01
影响因子：
3.2
通讯作者：
Verhegghe, Benedict
中科院分区：
文献类型：
--
作者：
De Santis, Gianluca;Mortier, Peter;Verhegghe, Benedict
患者特异性模拟被广泛用于研究局部血流动力学在现实形态。然而，预处理和网格生成是耗时的，依赖于操作员，并且最终网格的质量往往不是最优的。因此，提出了一种半自动的方法，用于患者特定的重建和从双翼血管造影的左冠状动脉树的结构化网格。使用新方法生成了7个六面体网格（50,000-3,200,000个单元），并与9个具有棱柱状边界层的非结构化四面体网格（150,000-3,100,000个单元）进行了比较。基于计算流体力学（CFD）的稳态血流模拟已被用于计算壁面剪切应力（WSS）。我们的结果（沿直线的99百分位，面积加权和局部WSS值）表明，六面体网格相对于四面体/棱镜网格收敛得更好，并且在相同的结果精度下，所需的单元数减少了6倍，计算时间减少了14倍。六面体网格优于四面体/棱镜网格，应优先用于计算WSS。
Patient-specific simulations are widely used to investigate the local hemodynamics within realistic morphologies. However, pre-processing and mesh generation are time consuming, operator dependent, and the quality of the resulting mesh is often suboptimal. Therefore, a semiautomatic methodology for patient-specific reconstruction and structured meshing of a left coronary tree from biplane angiography is presented. Seven hexahedral grids have been generated with the new method (50,000-3,200,000 cells) and compared to nine unstructured tetrahedral grids with prismatic boundary layer (150,000-3,100,000 cells). Steady-state blood flow simulation using Computational Fluid Dynamics (CFD) has been used to calculate the Wall Shear Stress (WSS). Our results (99 percentile, area-weighted and local WSS values along a line) demonstrate that hexahedral meshes with respect to tetrahedral/prismatic meshes converge better, and for the same accuracy of the result, six times less cells and 14 times less computational time are required. Hexahedral meshes are superior to tetrahedral/prismatic meshes and should be preferred for the calculation of the WSS.