An experimental study of the F wave in the baboon.
An experimental study of the F wave in the baboon.
复制标题
狒狒 F 波的实验研究。
DOI：
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发表时间：
1966
影响因子：
11
通讯作者：
S. Wray
中科院分区：
文献类型：
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作者：
J. McLeod;S. Wray
马格拉德里和麦克道格尔(1950)在人类身上表明，当尺神经在手腕处受到刺激时，从小鱼际肌记录到的肌肉动作电位，直接反应或M波紧随其后的是一个小偏转，即F波。这些作者认为F波是由于刺激周围神经的传入纤维引起的反射反应，但Dawson和Merton(1956)提出的证据表明，它是由向心性抽动引起的运动神经元在脊髓中反向激活后的放电引起的。索恩(1965)最近为这一观点提供了更多的证据。Gassel和Wiesendanger(1965)在猫的去传入足部肌肉中发现了一种具有F波某些特征的波，并得出结论，运动神经元的逆向激活有助于它的产生。由于F波潜伏期的测量在人类神经病的研究中可能具有诊断价值，因此了解其产生的生理机制是很重要的。本文介绍了实验结果，这些实验动物被选为实验动物，因为它们的前肢与人类的前肢在解剖上非常相似。在这些动物中，在前肢完全去传入后，从手部小肌肉记录到具有F波特征的动作电位，这些研究表明，F波的主要成分是脊髓运动神经元逆行激活的结果。
Magladery and McDougal (1950) showed in man that when the ulnar nerve is stimulated at the wrist and the muscle action potential recorded from the hypothenar muscles, the direct response or M wave is followed by a small deflection, the F wave. These authors considered that the F wave was a reflex response due to stimulation of afferent fibres in the peripheral nerve, but Dawson and Merton (1956) produced evidence that it resulted from the discharge of motor neurones in the spinal cord following their antidromic activation by centripetal volleys. Additional evidence for this view has recently been provided by Thorne (1965). Gassel and Wiesendanger (1965) found a wave with certain characteristics of the F wave in the deafferented foot muscles of cats, and concluded that antidromic activation of motor neurones contributed to its production. Since the measurement of the latency of the F wave may be of diagnostic value in the investigation of human neuropathy, it is important to understand the physiological mechanism by which it is produced. The present paper describes the results of experiments on baboons, which were selected as experimental animals because of the close anatomical resemblance of their forelimbs to those of man. In these animals, action potentials with the characteristics of F waves were recorded from the small muscles of the hand after complete deafferentation of the forelimb, and from these studies it is concluded that the main component of the F wave results from the antidromic activation of motor neurones in the spinal cord.