Genome‐wide transcriptional profiling analysis of all trans retinoic acid‐treated tongue carcinoma SCC‐9 cells

Genome‐wide transcriptional profiling analysis of all trans retinoic acid‐treated tongue carcinoma SCC‐9 cells
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DOI:
10.1002/jso.21998
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发表时间:
2011-12
影响因子:
2.5
通讯作者:
Yaohui Dai;Juan Wang;J. Xia;Yun Hong;Na Chen;B. Cheng
Yaohui Dai;Juan Wang;J. Xia;Yun Hong;Na Chen;B. Cheng
中科院分区:
医学3区
文献类型:
--
作者:
Yaohui Dai;Juan Wang;J. Xia;Yun Hong;Na Chen;B. Cheng

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全反式维甲酸(ATRA)被用作早幼粒细胞白血病的标准治疗。关于ATRA处理的舌癌细胞中的基因表达谱知之甚少。我们对ATRA处理的舌癌细胞进行了全基因组转录谱分析,以了解介导ATRA在舌癌中作用的途径。
All trans retinoic acid (ATRA) is used as standard of care in promyelocytic leukemia. Not much is known about the gene expression profile in ATRA‐treated tongue cancer cells. We performed a genome‐wide transcriptional profiling of ATRA‐treated tongue cancer cells to understand the pathways that mediate ATRA action in tongue cancer.