Psychophysiology of threat response, paradigm shifts in psychiatry, and RDoC: Implications for genetic investigation of psychopathology.
Psychophysiology of threat response, paradigm shifts in psychiatry, and RDoC: Implications for genetic investigation of psychopathology.
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DOI：
10.1111/psyp.12550
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发表时间：
2016-03
期刊：
影响因子：
3.7
通讯作者：
Hettema JM
中科院分区：
文献类型：
--
作者：
Hettema JM
本期的两篇文章试图进一步实现NIMH研究领域标准（RDoC）倡议的目标，即开发调查精神障碍的新方法，使用跨越传统障碍类别的基本维度，并与精神病理学的基础机制更紧密地结合起来。Lang、McTeague和Bradley的一篇文章描述了这种恐惧反应的无序交叉维度的构建。另一篇由Kozak和Cuthbert撰写，阐述了RDoC下研究对象的基础和概念。讨论了这些发展对精神病学遗传学研究的可能影响。
Two articles in this issue seek to further the goal of NIMH's Research Domain Criteria (RDoC) initiative to develop new approaches for investigating mental disorders, using fundamental dimensions that cut across traditional disorder categories and align more closely with mechanisms that underlie psychopathology. One article, by Lang, McTeague, and Bradley, describes the construction of such a disorder cross‐crossing dimension of fear response. The other, by Kozak and Cuthbert, expounds upon the basis and conceptualization of research targets under RDoC. Possible implications of these developments for psychiatric genetics research are discussed.