BIOLOGICAL IMPACT OF SMALL AIR IONS
BIOLOGICAL IMPACT OF SMALL AIR IONS
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DOI：
10.1126/science.959834
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发表时间：
1976-01-01
期刊：
影响因子：
56.9
通讯作者：
REED, EJ
中科院分区：
文献类型：
--
作者：
KRUEGER, AP;REED, EJ
有令人信服的证据表明，阴离子和阳离子都能抑制细菌和真菌在固体介质上的生长，当细胞和离子有机会接触时，对悬浮在水中的繁殖型细菌产生致命影响，并减少细菌气溶胶的活数量。通过物理作用，两种电荷中的任何一种离子都扰乱了雾化细菌悬浮液的稳定性，此外，还具有直接致死作用，负离子比阳离子更明显。关于空气离子作用的5-羟色胺假说，情况更为复杂。基本事实是，小鼠和大鼠对空气离子表现出与电荷相关的代谢反应，这种现象也发生在人类身上。由于5-羟色胺是一种如此有效的荷尔蒙，空气离子作用引起的最终功能变化令人印象深刻，并解释了Sharav综合征的迹象和症状。小鼠3种实验性呼吸道疾病的累积死亡率的变化也是电荷依赖的，阳离子通常会产生有害的影响。在感染流感病毒的小鼠中，离子剥夺会增加累积死亡率。由于离子耗竭是现代城市生活的一种持续伴随，因此可以推测对人类的类似有害影响。
There is convincing evidence that both negative and positive ions inhibit growth of bacteria and fungi on solid media, exert a lethal effect on vegetative forms of bacteria suspended in water when opportunity is provided for contact of cells and ions, and reduce the viable count of bacterial aerosols. Through physical action, ions of either charge upset the stability of aerosolized bacterial suspensions and, in addition, have a direct lethal effect which is more prominent with negative ions than with positive ions. With regard to the serotonin hypothesis of air ion action, the situation is more complex. The essential fact is that mice and rats display a charge-related metabolic response to air ions and this phenomenon also occurs in humans. Because serotonin is such a potent hormone, the ultimate functional changes incident to air ion action are impressive and account for the signs and symptoms of the Sharav syndrome. Alterations in the cumulative mortality rate with 3 experimental respiratory diseases in the mouse also are charge-dependent, positive ions routinely exercising a detrimental effect. In the case of mice infected with influenza virus, ion deprivation increases the cumulative mortality rate. Since ion depletion is a constant concomitant of modern urban life, comparable inimical effects on humans can be speculated.