Ulcerative esophagitis and ulcerative colitis.
Ulcerative esophagitis and ulcerative colitis.
复制标题
溃疡性食管炎和溃疡性结肠炎。
DOI：
10.1001/jama.1967.03130020086028
复制
发表时间：
1967
期刊：
影响因子：
--
通讯作者：
M. Sparberg
中科院分区：
文献类型：
--
作者：
K. B. Knudsen;M. Sparberg
致编辑：-溃疡性结肠炎是一种全身性疾病，经常累及皮肤、眼睛、关节和肝脏，不影响胃肠道的其他部位。摘要最近报告一例溃疡性结肠炎合并溃疡性食管炎及慢性肝炎的罕见病例。报告一例：1962年12月，一名15岁白人男孩出现广泛性黄斑丘疹、淋巴结病和脾肿大；随后出现间歇性发热、不适和水样腹泻。1964年1月，发现肝明显肿大，颈部及腋窝淋巴结肿大。总胆红素5 mg/100 ml，碱性磷酸酶22 Bodansky单位，血清总蛋白10.5 gm/100 ml，蛋白电泳显示γ-球蛋白弥漫性增高，范围为4.5 ~ 5.1 gm/100 ml（正常0.6 ~ 1.5 gm/100 ml）。超离心示γ-球蛋白以7S为主，巨球蛋白含量正常。血清谷草转氨酶水平在400 ~ 1000单位之间。乳胶凝集试验
To the Editor:— Ulcerative colitis is a systemic disease, frequently involving the skin, eyes, joints, and liver, without affecting other areas of the gastrointestinal tract. A most unusual example of ulcerative colitis associated with ulcerative esophagitis and chronic hepatitis was encountered recently. Report of a Case:— A generalized maculopapular eruption, lymphadenopathy, and splenomegaly developed in a 15-year-old white boy in December 1962; intermittent fever, malaise, and watery diarrhea followed. In January 1964, marked hepatomegaly and cervical and axillary lymphadenopathy were found. The total bilirubin was 5 mg/100 ml, alkaline phosphatase, 22 Bodansky units, and total serum protein, 10.5 gm/100 ml, with a diffusely increased γ-globulin on protein electrophoresis, ranging from 4.5 to 5.1 gm/100 ml (normal 0.6-1.5 gm/ 100 ml). Ultracentrifugation revealed that the γ-globulin was primarily 7S with a normal amount of macroglobulin. The serum glutamic oxaloacetic transaminase level ranged from 400 to 1,000 units. The latex agglutination test