Health and cognition among adults with and without Traumatic Brain Injury: A matched case-control study.

Health and cognition among adults with and without Traumatic Brain Injury: A matched case-control study.
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有和没有创伤性脑损伤的成年人的健康和认知:一项匹配的病例对照研究。

DOI:
10.1080/02699052.2022.2034190
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发表时间:
2022-02-23
期刊:
影响因子:
1.9
通讯作者:
Dams-O'Connor, Kristen
Dams-O'Connor, Kristen
中科院分区:
医学4区
文献类型:
--
作者:
Kumar, Raj G.;Ketchum, Jessica M.;Hammond, Flora M.;Novack, Thomas A.;O'Neil-Pirozzi, Therese M.;Silva, Marc A.;Dams-O'Connor, Kristen

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评估创伤性脑损伤(TBI)与健康状况之间的关系,并比较TBI病例和对照组之间的健康和认知关系。这项匹配的病例对照研究使用了来自TBI模型系统国家数据库(TBI病例)和美国中年(MIDUS)II和复习研究(对照)的数据。N=248例TBI病例与三个对照组的年龄、性别、种族和教育相匹配,没有替换。对病例组和对照组的18种自报疾病的患病率、自评健康状况、成人电话认知简易测试的综合评分进行比较。以下情况在TBI病例中比对照组明显更普遍:焦虑/抑郁(OR=3.12,95%CI:2.20,4.43,p<0.001),慢性睡眠问题(OR=2.76,95% CI:1.86,4.10,p<0.001)、头痛/偏头痛(OR=2.61,95% CI:1.50,4.54,p=0.0007)和卒中(OR=6.42,95% CI:2.93,14.10,p<0.001)。自评健康与认知之间的关系因TBI而显著变化(pinteraction=0.002)。与人口统计学上相似的未受伤的同龄人相比,TBI患者有更大的选择性神经行为状况的几率。在TBI患者中,与对照组相比,自测健康状况较差与认知之间存在更强的关联。TBI越来越被概念化为一种慢性疾病;目前的研究结果表明,TBI后的健康管理需要认知支持。
To evaluate associations between traumatic brain injury (TBI) and presence of health conditions, and to compare associations of health and cognition between TBI cases and controls. This matched case-control study used data from the TBI Model Systems National Database (TBI cases) and Midlife in the United States (MIDUS) II and Refresher studies (controls). N=248 TBI cases were age-, sex-, race-, and education-matched without replacement to three controls. Cases and controls were compared on prevalence of 18 self-reported conditions, self-rated health, composite scores from the Brief Test of Adult Cognition by Telephone. The following conditions were significantly more prevalent among TBI cases versus controls: anxiety/depression (OR=3.12, 95% CI: 2.20, 4.43, p<0.001), chronic sleeping problems (OR=2.76, 95% CI: 1.86, 4.10, p<0.001), headache/migraine (OR=2.61, 95% CI: 1.50, 4.54, p=0.0007), and stroke (OR=6.42, 95% CI: 2.93, 14.10, p<0.001). The relationship between self-rated health and cognition significantly varied by TBI (pinteraction=0.002). Individuals with TBI have greater odds of selected neurobehavioral conditions compared to their demographically-similar uninjured peers. Among persons with TBI there was a stronger association between poorer self-rated health and cognition than controls. TBI is increasingly conceptualized as a chronic disease; current findings suggest post-TBI health management requires cognitive supports.
DOI: 10.1037/0894-4105.9.1.80
发表时间: 1995-01-01
期刊: NEUROPSYCHOLOGY
影响因子: 2.4
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期刊: BRAIN INJURY
影响因子: 1.9
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期刊: NEUROPSYCHOLOGY
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