Comparison of polypropylene and polyethylene terephthalate (Dacron) meshes for abdominal wall hernia repair: a chemical and morphological study.

Comparison of polypropylene and polyethylene terephthalate (Dacron) meshes for abdominal wall hernia repair: a chemical and morphological study.
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DOI:
10.1007/s10029-004-0281-y
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发表时间:
2005-03-01
期刊:
Hernia : the journal of hernias and abdominal wall surgery
影响因子:
--
通讯作者:
Botto-Micca, F
Botto-Micca, F
中科院分区:
其他
文献类型:
--
作者:
Bracco, P;Brunella, V;Botto-Micca, F

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通过扫描电子显微镜(SEM)首次显示,用于腹壁疝修补术的聚丙烯(PP)切除网片(环氧乙烷灭菌)在物理上受到了极大的破坏,与植入时间无关,而聚对苯二甲酸乙二酯(PET)或涤纶(Dacron)网片(伽马辐射灭菌)没有因灭菌过程而改变,即使在长时间植入后也没有损坏。对PP和PET切除网状物及其环己烷提取物的傅里叶变换红外光谱(FTIR)研究表明,在植入期间,存在诸如角鲨烯、棕榈酸和硬脂酸等物种,在某些情况下,胆固醇从周围组织转移到聚合物中。在PP网眼的情况下,这些小的有机分子会降低材料的物理和机械性能。提出了一个假说来解释PET网状物的更好的行为(不是在临床意义上)。
For the first time, by scanning electron microscopy (SEM), polypropylene (PP) excised meshes (ethylene oxide sterilized) for abdominal wall hernia repair have been shown to be greatly damaged physically, independently of the implantation time, while the polyethylene terephthalate (PET), or Dacron, ones (gamma radiation sterilized), did not undergo alterations due to the sterilization process and were not damaged, even after long implantation periods. Fourier-Transform Infrared Spectroscopy (FTIR) study of PP and PET excised meshes, as well as of their extracts with cyclohexane, has shown the presence of species, such as squalene, palmitic and stearic acid, in some cases, cholesterol, transferred from the surrounding tissues to the polymer during the implantation period. In the case of PP meshes, these small organic molecules would reduce physical and mechanical properties of the material. A hypothesis is presented to account for the better behavior (not in the clinical sense) of PET meshes.