Reduced replication: a call to ARMS.
Reduced replication: a call to ARMS.
复制标题
减少复制：调用 ARMS。
DOI：
10.1016/j.cell.2005.02.028
复制
发表时间：
2005
期刊：
影响因子：
64.5
通讯作者：
Resnick,MichaelA
中科院分区：
文献类型：
--
作者：
Resnick,MichaelA
In this issue ofCell, Lemoine et al. (2005) monitor chromosome instability in yeast cells with reduced levels of an essential replicative DNA polymerase. The authors identify a hotspot for chromosome aberrations reminiscent of fragile sites in human cells. This hotspot is composed of inverted Ty elements, which lead to a double-strand break under conditions of limited replication.
