Development of fat digestion in infancy

Development of fat digestion in infancy
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DOI:
10.1136/fn.80.3.f183
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发表时间:
1999-05-01
影响因子:
4.4
通讯作者:
Weaver, LT
Weaver, LT
中科院分区:
医学1区
文献类型:
--
作者:
Manson, WG;Coward, WA;Weaver, LT

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目的:利用稳定同位素呼吸试验来测量生命早期脂肪消化的发展。方法:采用C-13标记的混合甘油三酯(MTG)对30例足月和早产儿进行纵向和横断相结合的研究。总共进行了76次测试。结果以6小时内恢复的累积剂量百分比(cPDR)表示。结果:在对30天以下婴儿进行的34项测试中,有18项显示cpdr低于成人和较大儿童的正常范围。对57日龄以上婴儿进行的其余测试均显示cpdr在正常范围内。峰值PDR相关性显著(r = 0.928, p
Aim-To measure the development of fat digestion in early life, using a stable isotope breath test.Methods-A combined longitudinal and cross sectional study was performed on 30 term and preterm infants using C-13- labelled mixed triglyceride (MTG). Seventy six tests were performed in all.Results were expressed as cumulative percentage dose recovered over 6 hours (cPDR). Results-Eighteen of 34 tests performed on infants under 30 days of age showed cPDRs below the normal range for adults and older children. The remainder of tests, performed on infants over 57 days of age, all showed cPDRs within the normal range. Peak PDR correlated significantly (r = 0.928, p