Anterior segment optical coherence tomography findings of presumed intraocular tuberculosis
Anterior segment optical coherence tomography findings of presumed intraocular tuberculosis
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DOI：
10.3109/15569527.2010.517231
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发表时间：
2011-03-01
影响因子：
1.6
通讯作者：
Ohguro, Nobuyuki
中科院分区：
文献类型：
--
作者：
Hashida, Noriyasu;Terubayashi, Aya;Ohguro, Nobuyuki
方法：一名 78 岁女性，因右眼持续性充血，疼痛持续 2 周，来我院就诊。注意到影响角膜周边的单侧基质角膜炎和伴有粘连的角肉芽肿、巩膜炎和前葡萄膜炎。由于患者的结核菌素皮试呈强阳性，她被诊断为疑似眼内结核。治疗前后采用AS-OCT监测眼前节解剖结构。结果：AS-OCT成像显示虹膜角膜角边界不清的不定形病变，角膜水肿，虹膜角膜角变窄、粘连，前房有渗出物和细胞。在实施每日抗结核治疗方案后，观察到角膜水肿得到改善，角膜厚度和渗出物减少。 AS-OCT 对于研究前粘连和角病变的范围很有用。结论：AS-OCT 可以对治疗反应进行非侵入性和非接触性分析，也有助于评估疾病活动性。
Methods: A 78-year-old woman with persistent right ocular injection and pain of 2 weeks'' duration was referred to our clinic. Unilateral stromal keratitis affecting the corneal periphery and angle granuloma with synechiae, scleritis, and anterior uveitis were noticed. Because of the patient''s intensely positive tuberculin skin test, she was diagnosed with presumed intraocular tuberculosis. The anatomic structures of the anterior segment were monitored by AS-OCT before and after the treatment.Results: AS-OCT imaging showed a poorly demarcated amorphous lesion in the iridocorneal angle, corneal edema, narrowing and synechiae of the iridocorneal angle, and anterior chamber exudates and cells. Improvement of the corneal edema and a decrease of corneal thickness and exudates were observed after implementation of a daily regimen of antituberculous treatment. AS-OCT was useful for investigating the extent of the anterior synechiae and angle lesions.Conclusions: AS-OCT allows noninvasive and noncontact analysis of the treatment response and is also useful to evaluate disease activity.