Analysis of buprenorphine by high-performance liquid chromatography.
Analysis of buprenorphine by high-performance liquid chromatography.
复制标题
DOI：
10.1016/s0021-9673(01)95515-3
复制
发表时间：
1985
期刊：
影响因子：
--
通讯作者：
I. Tebbett
中科院分区：
文献类型：
--
作者：
I. Tebbett
412 NOTES sample was extracted three times and the extracts combined. The organic phase was evaporated to dryness under a stream of nitrogen and the residue redissolved in 100~ 1 of methanol. Samples of 20~ 1 were injected onto the column. A straight line calibration graph was obtained for buprenorphine based on peak area measurements for concentrations of 2.5, 5.0, 10, 20, 50 and 100 ng/ml by addition of the drug to control serum and extraction by the procedure described above. Each point was taken as the average of two determinations.
