Endogenous cortical rhythms determine cerebral specialization for speech perception and production
Endogenous cortical rhythms determine cerebral specialization for speech perception and production
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DOI：
10.1016/j.neuron.2007.09.038
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发表时间：
2007-12-20
期刊：
影响因子：
16.2
通讯作者：
Laufs, Helmut
中科院分区：
文献类型：
--
作者：
Giraud, Anne-Lise;Kleinschmidt, Andreas;Laufs, Helmut
在多个时间尺度上，语音的声学特性与听觉和运动系统的节奏特性相匹配。音节率对应于自然的下颌相关的振荡节奏，和音位长度可以反映内源性振荡听觉皮层特性。言语的半球偏侧化可能是由于皮层调谐的不对称性，左、右听觉区对言语的频谱-时间特征的敏感度不同。使用同步脑电图（EEG）和功能性磁共振成像（fMRI）记录从人类，我们表明，自发的EEG功率变化的伽马范围内（音素率）与左侧听觉皮层突触活动的最佳相关性，而在θ范围内的波动最好的相关性在右侧。在这两个范围内的功率波动与嘴运动前区的活动相关，表明言语感知和产生的时间特性之间的耦合。这些数据表明，内源性皮质节律提供了时间和空间的限制的神经元机制的语音感知和生产。
Across multiple timescales, acoustic regularities of speech match rhythmic properties of both the auditory and motor systems. Syllabic rate corresponds to natural jaw-associated oscillatory rhythms, and phonemic length could reflect endogenous oscillatory auditory cortical properties. Hemispheric lateralization for speech could result from an asymmetry of cortical tuning, with left and right auditory areas differentially sensitive to spectro-temporal features of speech. Using simultaneous electroencephalographic (EEG) and functional magnetic resonance imaging (fMRI) recordings from humans, we show that spontaneous EEG power variations within the gamma range (phonemic rate) correlate best with left auditory cortical synaptic activity, while fluctuations within the theta range correlate best with that in the right. Power fluctuations in both ranges correlate with activity in the mouth premotor region, indicating coupling between temporal properties of speech perception and production. These data show that endogenous cortical rhythms provide temporal and spatial constraints on the neuronal mechanisms underlying speech perception and production.