Enantioselective aziridination reaction of α,β-unsaturated aldehydes using an organocatalyst and tert-butyl N-arenesulfonyloxycarbamates

Enantioselective aziridination reaction of α,β-unsaturated aldehydes using an organocatalyst and tert-butyl N-arenesulfonyloxycarbamates
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DOI:
10.1016/j.tetlet.2009.02.095
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发表时间:
2009-07-01
影响因子:
1.8
通讯作者:
Hamada, Yasumasa
Hamada, Yasumasa
中科院分区:
化学4区
文献类型:
--
作者:
Arai, Hiromi;Sugaya, Naomi;Hamada, Yasumasa

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描述了在二苯基脯氨醇三乙基甲硅烷基醚和碳酸钠或乙酸钠存在下,使用N-芳烃磺酰氧基氨基甲酸酯对包括芳香族底物的α,β-不饱和醛进行有机催化对映选择性氮丙啶化反应。
An organocatalytic enantioselective aziridination reaction of alpha,beta-unsaturated aldehydes including aromatic substrates using N-arenesulfonyloxycarbamates in the presence of diphenylprolinol triethylsilyl ether and sodium carbonate or sodium acetate is described.