Giant bilateral primary scrotal lipoma along with lipomas in multiple sites of the body: a case report and literature review.
Giant bilateral primary scrotal lipoma along with lipomas in multiple sites of the body: a case report and literature review.
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DOI：
10.21037/tau-20-1073
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发表时间：
2021-03
影响因子：
2
通讯作者：
Wei Q
中科院分区：
文献类型：
--
作者：
Zheng W;Shi M;Li T;Xu H;Chen Z;Wang X;Bai S;Le W;Yang L;Wei Q
阴囊间叶肿瘤在临床上极为少见，其中脂肪瘤是最常见的良性肿瘤。原发性阴囊脂肪瘤是指起源于阴囊壁的脂肪瘤。我们报告一位47岁男性，罹患双侧巨大原发性阴囊脂肪瘤沿着身体多个部位的脂肪瘤。阴囊超音波检查发现双侧阴囊内有巨大低回声肿块。对比增强计算机断层扫描（CT）显示阴囊区域脂肪密度增加。手术切除两个阴囊肿瘤。病理检查通过形态学观察以及荧光原位杂交（FISH）试验中无小鼠双微体2（MDM2）基因扩增证实了脂肪瘤的诊断。经过5个月的随访，患者伤口恢复良好，未观察到局部复发的迹象。根据文献回顾，迄今为止，在科学文献中报告的原发性阴囊脂肪瘤病例很少，这是首次报告双侧原发性阴囊脂肪瘤沿着身体多发性脂肪瘤。我们把这种情况作为一种罕见的现象。原发性阴囊脂肪瘤虽然少见，但临床医生在遇到类似阴囊病变时应予以考虑，并了解诊断方法及如何与其他疾病进行鉴别诊断，这与患者的治疗策略及预后有关。
Mesenchymal neoplasms of the scrotum are extremely rare in the clinical practices, in which lipoma is the most common benign neoplasm of them. Primary scrotal lipoma refers to the lipoma originated from scrotal wall. We reported a rare case of a 47-year-old man who suffered from bilateral giant primary scrotal lipoma along with lipomas in multiple sites of the body. Scrotal ultrasound indicated that huge hypoechogenic masses were observed in the bilateral scrotums. Contrast-enhanced computed tomography (CT) indicated increased fat density in the scrotal areas. Surgical resection was performed on both scrotal neoplasms. Diagnosis of lipoma was confirmed by the pathological examination through the morphological observation as well as the absence of murine double minute2 (MDM2) gene amplification in the fluorescence in situ hybridization (FISH) test. After five months of follow-up, the wound of the patient recovered well and no sign of local recurrence was observed. Based on the literature review, very few cases of primary scrotal lipoma were reported in the scientific literature up to date, and this is the first report of bilateral primary scrotal lipoma along with multiple lipomas of the body. We presented this case as a rare phenomenon. Although primary scrotal lipoma is rare, clinicians should take it into account when encountering similar scrotal lesions and know the methods for diagnosis and how to make differential diagnosis with other diseases, which is associated with the patient's treatment strategy and prognosis.
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影响因子：
2.6
作者：
Szmigielski, W;Khairat, M;Ejeckam, GC
通讯作者：
Ejeckam, GC
影响因子：
2.1
作者：
HUNTER, JC;JOHNSTON, WH;GENANT, HK
通讯作者：
GENANT, HK
影响因子：
1.2
作者：
Nikolic, Zivorad S.;Jeremic, Jelena V.;Stojnic, Jelena D.
通讯作者：
Stojnic, Jelena D.
影响因子：
5.5
作者：
Gupta, Pushpender;Potti, Tommy A.;Pacholke, David A.
通讯作者：
Pacholke, David A.
影响因子：
2.1
作者：
Kim, Sun-Ouck;Im, Chang Min;Ryu, Soo Bang
通讯作者：
Ryu, Soo Bang