NUTRITIONALANAEMIA AND MALARIA IN PRE-SCHOOL AND SCHOOL AGE CHILDREN
NUTRITIONALANAEMIA AND MALARIA IN PRE-SCHOOL AND SCHOOL AGE CHILDREN
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DOI：
10.4103/1596-3519.55690
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发表时间：
2008-03-01
影响因子：
0.9
通讯作者：
Keshinro, O.
中科院分区：
文献类型：
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作者：
Anumudu, C.;Afolami, M.;Keshinro, O.
背景：贫血最常见的原因是缺铁，但也可能是叶酸、维生素B-12和蛋白质缺乏所致。有些贫血不是营养因素引起的，而是先天因素和寄生虫病如疟疾引起的。本研究旨在评估Odogbolu地方政府地区两个农村地区学龄前和学龄儿童贫血的患病率，并确定其原因是否是营养性的或可归因于malia.Methods：共177名2至11岁的儿童被纳入研究。通过显微镜检查儿童的疟疾寄生虫。使用世界卫生组织（WHO）血红蛋白和红细胞压积的年龄调整临界值对贫血进行分类。血清铁蛋白的酶联免疫吸附试验与标准方法测定铁缺乏进行了比较。营养不良（发育迟缓、消瘦和体重不足）根据国家卫生统计中心的标准进行分类。以下数值？- 2SD定义为轻-中度营养不良，结果：87.1%的儿童贫血，95%的儿童血红蛋白低于11g/dl，但寄生虫感染率和密度较低。营养不良是明显的; 36%的儿童发育不良，18.3%消瘦，44.2%体重不足。血清铁蛋白对贫血的诊断较PCV敏感。虽然男孩和学龄前儿童的贫血率高于女孩和学龄儿童，但仅学龄前儿童的差异显著（P =.004）。贫血症也显着较高，在Mallwo村学校比在伊洛蒂（P =.0001）结论：在这一人群中检测到的贫血可能是由于营养不足，而不是疟疾。
Background: The most common cause of anemia is a deficiency of iron; but it may also be caused by deficiencies of folates, vitamin B-12 and protein. Some anemias are not caused by nutritional factors, but by congenital factors and parasitic diseases such as malaria. This study attempted to estimate the prevalence of anemia among pre-school and school-aged children in two rural areas of Odogbolu Local government area, and to determine whether its cause was nutritional or could be attributed to malaria.Methods: A total of 177 children between the ages of 2 and 11 years were included in the study. Children were examined for malaria parasites by microscopy. The World Health Organization (WHO) age-adjusted cut-off for hemoglobin and hematocrit were used to classify anemia. An enzyme linked immunosorbent assay for serum ferritin was compared with standard methods of determining iron deficiency. Under-nutrition (stunting, wasting and underweight) was classified according to the National Centre for Health Statistics standards. Values below ?-2SD were defined as mild-moderate under-nutrition, and those below ?-3SD as severe malnutrition.Results: Most of the children were anemic, 87.1%, having PCV values below the 32% cut-off and 95% with hemoglobin levels lower than the 11g/dl, although parasite prevalence and density were low. Malnutrition was patent; 36% of the children were stunted, 18.3% wasted and 44.2% underweight. Serum ferritin was more sensitive than PCV in detecting anemic children. Although anemia was higher in boys and preschoolers compared to girls and school aged children, the difference was significant only in preschoolers (P =.004). Anaemia was also significantly higher in Irawo village school than in Iloti (P =.0001)Conclusion: The anemia detected in this population may be due more to under-nutrition than to malaria.