Positive effect of early loading on implant stability in the bi-cortical guinea-pig model
Positive effect of early loading on implant stability in the bi-cortical guinea-pig model
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DOI：
10.1111/j.1600-0501.2005.01156.x
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发表时间：
2005-08-01
影响因子：
4.3
通讯作者：
Naert, I
中科院分区：
文献类型：
--
作者：
De Smet, E;Jaecques, S;Naert, I
种植体植入后早期的加载在牙科中得到了迅速的关注。当施加即刻和早期植入物载荷时，通过共振频率仪器定义的主要植入物稳定性已被分离为预测因素。本研究的目的是通过共振频率分析（RFA）研究早期（7天后）机械负荷对骨整合建立的影响。经皮钛植入物安装在10只豚鼠的两个胫骨。种植体安装后一周，每天加载一个种植体（测试），持续6周，而对侧作为未加载的种植体（对照）。以3 Hz的频率和5 N的力振幅施加正弦变化的弯曲力矩，持续1800个循环。在植入物安装时测量共振频率，从那时起每周使用RFA装置（Osstell（R））测量共振频率。与对照植入物相反，对照植入物在安装后1周显示出稳定性降低，在3周时达到最小值（~ 200 Hz），测试植入物显示出稳定性随时间的推移逐渐增加。6周后，试验和对照种植体的平均共振频率达到相同值。正如最近的文献所证实的那样，早期加载并不一定会危及钛种植体骨结合的建立。相反，通过RFA测量确定，控制载荷有利于在早期关键愈合期保持种植体稳定性。
Loading, early after implant placement, has gained rapid interest in dentistry. Primary implant stability, as e.g. defined by resonance frequency instrumentation, has been isolated as a predicator when immediate and early implant loading is applied. The aim of this study was to investigate the effect of early (after 7 days) mechanical loading on the establishment of osseointegration by means of resonance frequency analysis (RFA). Percutaneous titanium implants were installed in both tibiae of 10 guinea-pigs. One week after implant installation, one implant (test) was loaded daily for 6 weeks, while the contra-lateral served as the unloaded one (control). A sinusoidally varying bending moment was applied at a frequency of 3 Hz and a force amplitude of 5 N, for 1800 cycli. Resonance frequency was measured at implant installation and from then on weekly using the RFA-device (Osstell (R)). Contrary to control implants, that showed a decrease in stability 1 week after installation, reaching a minimum at 3 weeks (-200 Hz), test implants showed a progressive increase in stability over time. After 6 weeks, the mean resonance frequency of test and control implants reached the same values. As confirmed by recent literature, early loading does not have to endanger the establishment of osseointegration of titanium implants. On the contrary, controlled loading is beneficial to maintain the implant stability during the early critical healing period as determined by RFA-measurements.