Thyroid hormone binding protein contains glycosylation site binding protein activity.
Thyroid hormone binding protein contains glycosylation site binding protein activity.
复制标题
甲状腺激素结合蛋白含有糖基化位点结合蛋白活性。
DOI：
10.1016/0006-291x(90)90538-x
复制
发表时间：
1990
影响因子：
3.1
通讯作者：
Lennarz,WJ
中科院分区：
文献类型：
--
作者：
Kimura,H;Noiva,R;Mizunaga,T;Yamauchi,K;Horiuchi,R;Cheng,SY;Lennarz,WJ
Several lines of evidence provided by other workers indicate that within the same species thyroid hormone binding protein, the β-subunit of prolyl hydroxylase, and protein disulfide isomerase are the same protein. We sought to determine if glycosylation site binding protein, a lumenal protein of the endoplasmic reticulum, also has the same primary structure. To accomplish this the level of glycosylation site binding protein (GSBP) activity, measured by photolabeling with a glycosylation site peptide probe, was carried out in preparations of 3T3 cells and in E. coli transformed with human thyroid hormone binding protein cDNA. The results strongly support the idea that GSBP is identical to these other lumenal proteins of the endoplasmic reticulum.
