Long-term patch recordings from adult spinal neurons herald new era of opportunity.
Long-term patch recordings from adult spinal neurons herald new era of opportunity.
复制标题
成人脊髓神经元的长期斑块记录预示着新机遇时代的到来。
DOI:
10.1152/jn.00873.2011
复制
发表时间:
2011
影响因子:
2.5
通讯作者:
Hochman,Shawn
中科院分区:
文献类型:
--
作者:
Hochman,Shawn
Recently, Andreas Husch, Nathan Cramer, and Ronald M. Harris-Warrick achieved a remarkable breakthrough in patch-clamp recordings of ventral horn neurons in the adult spinal cord slice preparation. This landmark study that breaks the “age barrier” is titled “Long-duration perforated patch recordings from spinal interneurons of adult mice” (Husch et al., in press). In it, the authors demonstrate the unprecedented ability to undertake day-long (up to 12 h), and utterly stable perforated patch recordings. A description of the methodology is detailed in their paper. Here, I give a brief overview before providing context to this extraordinary achievement.