Iontophoresis of 22NA and 131-I into the inner ear.
Iontophoresis of 22NA and 131-I into the inner ear.
复制标题
将 22NA 和 131-I 离子导入内耳。
DOI：
10.1001/archotol.1966.00760020215006
复制
发表时间：
1966
影响因子：
--
通讯作者：
D. Cody
中科院分区：
文献类型：
--
作者：
R. Stecker;D. Cody
Iontophoresis是“…溶液中的物质通过电流作用于身体表面并进入组织的过程。“1自1918年以来，离子电渗疗法一直用于治疗中耳疾病。[2] 1955年，Rius和Martinez Visca [3]和Schenk [4]分别主张使用离子电渗疗法治疗内耳疾病。Rius通过经鼓膜离子导入妥拉苏林（Priscoline）治疗梅尼埃病和内耳的“血管异常”。在所有病例中，3，5他注意到眩晕和耳鸣减轻，听力改善。Schenk 4报道了用氯化氨甲酰胆碱（Doryl）进行耳离子电渗治疗后梅尼埃病患者的症状改善，然而，他提出了一个问题，是否有任何药物实际上到达内耳，或者这种效果仅仅是由于电流引起的？临床观察表明，局部麻醉剂放置在人的鼓室
IONTOPHORESIS is the "... process wherein substances in solution are applied to the surface of the body and introduced into the tissues by the use of electrical current." 1 Iontophoresis has been used to treat middle ear disorders since 1918. 2 In 1955, Rius and Martinez Visca 3 and Schenk 4 independently advocated the use of iontophoresis for the treatment of diseases of the inner ear. Rius treated Meniere's disease and "vascular abnormalities" of the inner ear by transtympanic iontophoresis of tolazoline (Priscoline). In all cases, 3,5 he noted relief of vertigo and tinnitus and improvement of hearing. Schenk 4 reported symptomatic improvement of patients with Meniere's disease after aural iontophoresis with carbamylcholine chloride (Doryl) However, he raised the question, Does any medication actually reach the inner ear or is the effect due to electric current alone? Clinical observations have shown that local anesthetics placed in the human tympanic cavity