Determinants of participation in state‐of‐the‐art cancer prevention, early detection/screening, and treatment trials among African‐Americans
Determinants of participation in state‐of‐the‐art cancer prevention, early detection/screening, and treatment trials among African‐Americans
复制标题
非裔美国人参与最先进的癌症预防、早期检测/筛查和治疗试验的决定因素
作者：
S. Millon
有人认为，通过积极实施预防、诊断和最先进的治疗方案，以及增加对癌症试验的参与，可以实现降低高危人群癌症死亡率的最大潜力。然而，国家数据表明，非洲裔美国人在这些项目和/或试验中的代表性往往不足。许多因素被认为有助于这种情况，但目前很少有研究已经进行，以验证其影响。因此，进行了一项研究，重点是确定有助于非洲裔美国人参与研究性癌症项目和/或试验的因素。220名非洲裔美国男性和女性被招募参加一项区域调查。有证据支持的影响，看法，态度和信仰的意愿参加研究项目和/或试验。对参与研究项目和/或试验的意愿影响最大的因素是研究项目和/或试验的感知疗效。在这一样本中，许多人对参与研究计划和/或试验明显犹豫不决。普遍认为这些项目和/或试验只针对那些患有所研究疾病或病症的人，这似乎影响了他们的反应。然而，当向参与者提供关于一般社区内的人（特别是高风险者）参与预防、诊断和治疗方案和/或项目的机会以及参与的好处的信息时，参与者表示更愿意参与。
It has been suggested that the greatest potential for reducing cancer mortality in high-risk populations may be realized through aggressive implementation of prevention, diagnostic, and state-of-the-art treatment programs and increasing participation in cancer trials. However, the national data suggest that African-Americans are most often underrepresented in such programs and/or trials. Multiple factors are assumed to contribute to this situation, but currently few studies have been conducted to validate their influence. A study focused on identifying factors that contribute to participation of African-Americans in investigational cancer programs and/or trials was therefore conducted. Two hundred twenty African-American men and women were recruited to participate in a regional survey. There was evidence to support the impact that perceptions, attitudes, and beliefs have on willingness to participate in investigational programs and/or trials. The factor having the greatest influence on willingness to participate in investigational programs and/or trials was perceived efficacy of the investigational programs and/or trials. Among this sample there was an apparent hesitancy of many to participate in research programs and/or trials. The prevailing belief that such programs and/or trials were only for those with the disease or condition under study appeared to influence their response. However, when provided information on the opportunities for participation in prevention, diagnostic, and treatment programs and/or projects for those within the general community (especially for those at higher risk) and on the benefits of participation, a much greater willingness to participate was expressed by participants.