3-methoxycarbonyl-5-nitrophenyl boronic acid: high affinity diol recognition at neutral pH
3-methoxycarbonyl-5-nitrophenyl boronic acid: high affinity diol recognition at neutral pH
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DOI：
10.1016/j.bmcl.2003.10.017
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发表时间：
2004-01-05
影响因子：
2.7
通讯作者：
Basu, A
中科院分区：
文献类型：
--
作者：
Mulla, HR;Agard, NJ;Basu, A
对几种硼酸进行了筛选，以确定它们与二醇的结合能力。3-甲氧基甲酰基-5-硝基苯基硼酸与邻甲氨基取代的硼酸的亲和力与邻甲氨基基取代的硼酸相当，与邻苯二酚染料和果糖结合。这项工作表明，适当官能化的缺电子硼酸在二醇和碳水化合物的识别中具有更大的作用。(C)2003爱思唯尔有限公司。保留所有权利。
Several boronic acids were screened for their ability to bind to diols. 3-Methoxycarbonyl-5-nitrophenyl boronic acid bound to both a catechol dye as well as fructose with a comparable affinity to that of an ortho-methylamino substituted boronic acid. This work suggests a greater role for appropriately functionalized electron deficient boronic acids in diol and carbohydrate recognition. (C) 2003 Elsevier Ltd. All rights reserved.