Herbal Medicine Prescriptions for Functional Dyspepsia: A Nationwide Population-Based Study in Korea.
Herbal Medicine Prescriptions for Functional Dyspepsia: A Nationwide Population-Based Study in Korea.
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DOI：
10.1155/2022/3306420
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Yang C
中科院分区：
文献类型：
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作者：
Lee B;Ahn EK;Yang C
在东亚国家，草药被广泛用于治疗功能性消化不良(FD)。本研究旨在通过对近10年来韩国国民医保报销数据的分析，分析韩医临床对FD患者的中药处方模式，并考察国民医保范围内对FD患者使用中药的情况。对2010-2019年所有向健康保险审查和评估服务声称患有FD的处方数据和草药处方进行了审查。我们估计了每种草药的人口统计学、临床特征、年处方量和费用。通过分析与FD一起使用的韩国标准疾病分类代码的频率，调查FD的常见并存情况。总共确定了19,388,248个草药处方。中草药处方主要由妇女、老年人、韩国医学诊所的门诊病人和国家医疗保险申请，这一数字每年都在增加。处方频率最高的中草药是平胃散(31.12%)，其次是香砂平胃散(23.20%)、琼夏汤(贡嘎汤)(6.31%)、半夏泻心汤(6.25%)。中药处方总费用呈逐年上升趋势，其中香砂平胃散最高(19.37%)，半夏泻心汤(半夏泻心汤)次之(17.50%)，平胃散(15.63%)次之。肌肉骨骼和结缔组织疾病包括下腰痛和肌痛是与FD相关的最常见的并发症。这是第一次使用索赔数据调查FD的疾病负担和草药实际处方模式的研究。未来的临床研究和相关的医疗保健政策应该建立在我们的研究基础上。
Herbal medicine is widely used for the treatment of functional dyspepsia (FD) in East Asian countries. We aimed to analyze the prescription patterns of herbal medicine for patients with FD in Korean medicine clinical settings through the analysis of national health insurance claims data over the past 10 years and to check how herbal medicine has been used for FD within the scope of national health insurance. All prescription data claimed to the Health Insurance Review and Assessment Service with the diagnosis of FD and herbal medicine prescriptions in 2010–2019 were reviewed. We estimated the demographics, clinical characteristics, and annual prescription amount and cost of each herbal medicine. Frequent comorbidities of FD were investigated by analyzing the frequency of the Korean standard classification of diseases codes used together with FD. In total, 19,388,248 herbal medicine prescriptions were identified. Herbal medicine prescriptions were mostly claimed by women, the elderly, outpatients at Korean medicine clinics, and national health insurance; the number increased every year. The most frequently prescribed herbal medicine was Pingwei-san (Pyeongwi-san) (31.12%), followed by Xiangshapingwei-san (Hyangsapyeongwi-san) (23.20%), Qiongxia-tang (Gungha-tang) (6.31%), and Banxiaxiexin-tang (Banhasasim-tang) (6.25%). The total cost of herbal medicine prescriptions increased every year, and it was highest for Xiangshapingwei-san (Hyangsapyeongwi-san) (19.37%), followed by Banxiaxiexin-tang (Banhasasim-tang) (17.50%) and then Pingwei-san (Pyeongwi-san) (15.63%). Musculoskeletal and connective tissue diseases including low back pain and myalgia were the commonest comorbidities associated with FD. This is the first study to investigate the disease burden and actual prescription pattern of herbal medicine for FD using claim data. Future clinical research and related healthcare policies should be established based on our study.