Smoking deterrence using silver acetate.
Smoking deterrence using silver acetate.
复制标题
使用醋酸银戒烟。
DOI：
10.1176/ps.44.2.113
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Frances,RJ
中科院分区：
文献类型：
--
作者：
Hymowitz,N;Feuerman,M;Hollander,M;Frances,RJ
背景：关于醋酸银威慑疗法的文献已在其他地方进行了综述(4)，这里只提及几项研究。其中最成功的一项是马尔科姆及其同事的研究(6)，他们报告说，受试者每天6次使用6毫克醋酸银薄荷口香糖，持续三周，即推荐的疗法(7)，戒烟率为11.1%，明显高于安慰剂组4%的戒烟率。戒烟率是通过测量血液中的糖化血红蛋白水平来确认的。在丹麦，Jensen和他的同事们专门讨论了长期戒烟的问题。他们对496名吸烟者进行了为期一年的跟踪调查，通过呼出的一氧化碳来衡量吸烟状况。吸烟者有一周的时间自行戒烟，之后戒烟者被随机分配到尼古丁口香糖、6 mg醋酸银口香糖或普通口香糖治疗1~2周。Jensen和他的同事的早期研究表明，6毫克的醋酸银口香糖(Tabmint)可以安全地每天使用6次，持续12周，而不会有银屑病的风险。除了口香糖
Background The literature on silver-acetate deterrent therapy has been reviewed elsewhere (4), and only a few studies will be mentioned here. One of the most successful was the study by Malcolm and colleagues(6), who reported that subjects who used the 6 mg silver-acetate gum Tabmint six times per day for three weeks, the recommended regimen (7), had a smoking cessation rate of 1 1 percent, which was significantly higher than the rate of 4 percent for subjects in the placebo group. Quit rates were confirmed by measurement of blood car-boxyhemoglobmn levels.In Denmark, Jensen and associates (8) specifically addressed the issue of long-term smoking cessation. They followed 496 smokers for one year, measuring smoking status by expired-air carbon monoxide. Smokers were given one week to quit smoking on their own, after which the ex-smokers were assigned randomly to 1 2-week therapy with nicotine gum, 6 mg silver-acetate gum, or ordinary gum. Earlier studies by Jensen and colleagues(9) showed that the 6 mg silver-acetate gum (Tabmint) could be used safely six times per day for 1 2 weeks without risk ofargyrism. In addition to gum