Evaluation of Takayasu arteritis activity by delayed contrast-enhanced magnetic resonance imaging

Evaluation of Takayasu arteritis activity by delayed contrast-enhanced magnetic resonance imaging
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DOI:
10.1016/j.ijcard.2010.10.002
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发表时间:
2012-03-08
影响因子:
3.5
通讯作者:
Ma, Lili
Ma, Lili
中科院分区:
医学2区
文献类型:
--
作者:
Jiang, Lindi;Li, Dan;Ma, Lili

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背景:通过磁共振血管成像(MRA)定量检测和评估大动脉炎(TA)的疾病活动性。方法:将26例大动脉炎患者分为活动组和非活动组。所有患者均行延迟增强MRI检查。受累血管分为A型(主动脉及其弓的主要分支)和B型(二级或三级分支)。结果:活动期患者左锁骨下动脉狭窄程度明显高于非活动期患者(14/16,87.5%vs.2/10,20%;P
Background: To measure and assess the disease activity of Takayasu arteritis (TA) quantitatively by magnetic resonance angiography (MRA).Methods: Twenty-six Chinese TA patients were divided into an active group and an inactive group. All patients underwent delayed contrast-enhanced MRI. The vessels involved were categorized into type A (main branches of aorta and its arch) and type B (secondary or tertiary branches). Three quantitative scores were defined to gauge lumen stenosis, vessel wall thickness, and vessel wall enhancement, and compared between groups and types.Results: The patients in the active group had more stenosis in left subclavian artery than those in the inactive group (14/16, 87.5% vs. 2/10, 20%; p