Y-CHROMOSOME-SPECIFIC DNA AMPLIFIED IN ANCIENT HUMAN BONE
Y-CHROMOSOME-SPECIFIC DNA AMPLIFIED IN ANCIENT HUMAN BONE
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DOI：
10.1007/bf01134353
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发表时间：
1991-06-01
影响因子：
--
通讯作者：
HERRMANN, B
中科院分区：
文献类型：
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作者：
HUMMEL, S;HERRMANN, B
从过去的种群和个体中发现基因决定的特征一直是现代体质人类学的兴趣焦点。对古血清学[1]和离散形态特征[2]的兴趣是由于对群体遗传学和亲缘关系的动态感兴趣。聚合酶链反应（polymerase chain reaction， PCR）[3]的发展及其高灵敏度[4,5]，现在提供了直接在分子水平上获得遗传信息的可能性，甚至从古老的来源材料[6,7]。Hagelberg [8], Horai et al.[9]和H~ inni et at.[9]首次报道了从考古骨骼中提取和扩增线粒体DNA。最近，从7500年前的视窗人脑中成功扩增出HLA基因的研究已被报道。
The discovery of genetically determined characters from past populations and individuals has always been a focus of interest within modern physical anthropology. The interest in paleoserology [1] as well as in discrete morphological traits [2] was due to interest in the dynamics of population genetics and kinship.The development of the polymerase chain reaction (PCR)[3] and its high sensitivity [4, 5] now provides the possibility to obtain genetic information directly on a molecular level even from ancient source material [6, 7]. The extraction and amplification of mitochondrial DNA from archaeological bone were first reported by Hagelberg [8], Horai et al.[9], and H~ inni et at.[10]. Most recently, the successful amplification of HLA genes from the 7500-year-old Windover brain has been reported [11].