A novel (2,2-Diarylvinyl)phosphine/palladium catalyst for effective aromatic amination
A novel (2,2-Diarylvinyl)phosphine/palladium catalyst for effective aromatic amination
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DOI：
10.1002/adsc.200700220
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发表时间：
2007-09-01
影响因子：
5.4
通讯作者：
Kobayashi, Tohru
中科院分区：
文献类型：
--
作者：
Suzuki, Ken;Hori, Yoji;Kobayashi, Tohru
设计并合成了一系列新的二芳基乙烯基膦配体。由配体和钯物种组成的催化剂体系有效地催化了芳基溴和芳基氯与胺的偶联反应，以良好至优异的产率得到相应的产物。该效率可能来自钯中心与二芳基乙烯基膦配体上的顺式-芳基部分之间的相互作用，从而在偶联反应期间稳定催化中间体。
A new series of diarylvinylphosphine ligands was designed and synthesized. A catalyst system, consisting of the ligands and palladium species, effectively catalyzed the coupling reaction of aryl bromides and chlorides with amines to afford the corresponding products in good to excellent yields. The efficiency is likely derived from an interaction between the palladium center and the cis-aryl moiety on the diarylvinylphosphine ligand stabilizing a catalytic intermediate during the coupling reaction.