SUPRASPINAL CONTROL OF INTERNEURONES MEDIATING SPINAL REFLEXES
SUPRASPINAL CONTROL OF INTERNEURONES MEDIATING SPINAL REFLEXES
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DOI：
10.1113/jphysiol.1959.sp006262
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发表时间：
1959-01-01
影响因子：
5.5
通讯作者：
LUNDBERG, A
中科院分区：
文献类型：
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作者：
ECCLES, RM;LUNDBERG, A
方法以硫喷妥钠或乙醚为麻醉剂，对去脑丘间切断法的猫进行实验。当动物被安装在框架中并完成所有其他解剖时，就进行去大脑。在大多数实验中，脊髓横断发生在局部注射可卡因后的第一个腰椎节段。将特别参考脐带更多地向喙分开的实验。由于所用的分析都是短效的，因此结果可能被认为是来自几乎没有麻醉的动物。在大多数实验中，突触活动是通过它们在腹根记录的单突触反射的活动来衡量的(Renshaw，1940；Lloyd，1941,1946a)。在一些实验中，细胞内的记录来自运动神经元，兴奋性和抑制性突触后电位(EPSP和IPSP)给出了各自突触活动的直接测量(Eccle，Eccle&Lundberg，1957a，b，c；Eccle&Lundberg，1959)。为了投资-
METHODS These experiments were done on cats decerebrated by intercollicular section, using pentothal or ether as the anaesthetic. The decerebration was performed when the animal had been mounted in the frame and all other dissection had been completed. In most experiments transection of the spinal cord was made in the first lumbar segment after local injection of cocaine. Special reference will be made to the experiment in which the cord was divided more rostrally. Since the anaes-thetics employed were all short-acting the results may be considered to be from animals virtually unanaesthetized.In most of the experiments the synaptic actions were measured by their action on testing mono-synaptic reflexes recordedin the ventral roots (Renshaw, 1940; Lloyd, 1941, 1946a). In some experiments intracellular records were taken from motoneurones, the excitatory and inhibitory post-synaptic potentials (EPSP and IPSP) giving a direct measure of the respective synaptic actions (Eccles, Eccles & Lundberg, 1957a, b, c; Eccles & Lundberg, 1959). In order to investi-