Abnormal ratio of CD57+ cells to CD56+ cells in women with recurrent implantation failure
Abnormal ratio of CD57+ cells to CD56+ cells in women with recurrent implantation failure
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反复着床失败女性 CD57( ) 细胞与 CD56( ) 细胞比例异常
DOI：
10.1111/aji.12708
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发表时间：
2017-11-01
影响因子：
3.6
通讯作者：
Sun, Haixiang
中科院分区：
文献类型：
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作者：
Jiang, Ruiwei;Yan, Guijun;Sun, Haixiang
为了更好地了解复发性着床失败（RIF）妇女的自然杀伤（NK）细胞及其与调节性T细胞（TCFs）的关系，定义一个更精确的参数。CD 57+细胞和Foxp 3 +应用免疫细胞化学和流式细胞术对23例正常人和32例RIF患者的子宫内膜和外周血中的细胞进行检测。RIF组子宫内膜中CD 57 +/CD 56+细胞比值显著升高（P
ProblemTo define a more precise parameter for a better understanding of natural killer (NK) cells and its relation with regulatory T cells (Tregs) in women with recurrent implantation failure (RIF).Method of studyThe percentages of CD56+ cells, CD57+ cells and Foxp3+ cells in the endometrium and blood from 23 normal controls and 32 women with RIF were measured by immunocytochemistry and flow cytometry.ResultsWomen with RIF had significantly increased ratio of CD57+ cells to CD56+ cells in both the endometrium (P