Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions.
Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions.
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DOI：
10.1136/vr.103593
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发表时间：
2016-03-12
期刊：
影响因子：
--
通讯作者：
Dixon L
中科院分区：
文献类型：
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作者：
Guinat C;Gogin A;Blome S;Keil G;Pollin R;Pfeiffer DU;Dixon L
非洲猪瘟（ASF）是欧洲养猪业的主要威胁。 2007年以来，非洲猪瘟疫情在高加索、东欧和波罗的海国家持续爆发，给许多养猪户和猪肉生产者造成严重经济损失。此外，过去几年，野猪种群中非洲猪瘟病例数量急剧增加。有证据表明，直接接触具有传染性的家猪和野猪以及食用受污染的饲料是非洲猪瘟病毒（ASFV）向家猪传播的主要途径。然而，巨大的知识差距凸显了迫切需要研究通过环境间接传播的动态、摄入受污染饲料的最低感染剂量、传染性野猪和家猪之间有效接触的可能性、康复动物成为携带者和传播储存库的可能性、病毒在野猪种群中的潜在持久性以及人类行为对非洲猪瘟病毒传播的影响。这将为优化当前的干预措施和开发新的工具和策略提供更好的科学依据，以降低非洲猪瘟病毒传播给家猪的风险。
African swine fever (ASF) is a major threat to the pig industry in Europe. Since 2007, ASF outbreaks have been ongoing in the Caucasus, Eastern Europe and the Baltic countries, causing severe economic losses for many pig farmers and pork producers. In addition, the number of ASF cases in wild boar populations has dramatically increased over the past few years. Evidence supports direct contact with infectious domestic pigs and wild boars, and consumption of contaminated feed, as the main transmission routes of ASF virus (ASFV) to domestic pigs. However, significant knowledge gaps highlight the urgent need for research to investigate the dynamics of indirect transmission via the environment, the minimal infective doses for contaminated feed ingestion, the probability of effective contacts between infectious wild boars and domestic pigs, the potential for recovered animals to become carriers and a reservoir for transmission, the potential virus persistence within wild boar populations and the influence of human behaviour for the spread of ASFV. This will provide an improved scientific basis to optimise current interventions and develop new tools and strategies to reduce the risk of ASFV transmission to domestic pigs.