Modified constraint-induced therapy in chronic stroke: Results of a single-blinded randomized controlled trial

Modified constraint-induced therapy in chronic stroke: Results of a single-blinded randomized controlled trial
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DOI:
10.2522/ptj.20060029
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发表时间:
2008-03-01
期刊:
影响因子:
3.2
通讯作者:
Kissela, Brett M.
Kissela, Brett M.
中科院分区:
医学2区
文献类型:
--
作者:
Page, Stephen J.;Levine, Peter;Kissela, Brett M.

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背景和目的本单盲随机对照试验比较了可报销的门诊患者改良强制诱导治疗(mCIT)方案的疗效(每周3天进行半小时治疗,其中受试者每周5天使用受影响较大的手臂结合受影响较小的手臂限制,持续5小时;这两种方案均在10周期间施用),对于受影响更严重的手臂采用时间匹配的锻炼方案,或者采用无治疗对照方案。研究对象35例慢性脑卒中患者参加了本研究。方法采用行动研究手臂测验(ARAT)、Fugl-Meyer卒中后运动恢复评估(FM)和运动活动日志(MAL)对受试者进行评估。讨论和结论这些数据肯定了以前的发现,表明这种可报销的门诊方案增加了更多受影响的手臂使用和功能。变化幅度与更强方案(如强制诱导治疗)中报告的变化幅度一致。
Background and PurposeThis single-blinded randomized controlled trial compared the efficacy of a reimbursable, outpatient, modified constraint-induced therapy (mCIT) protocol (half-hour therapy sessions occurring 3 days per week in which subjects used the more affected arm combined with less affected arm restriction 5 days per week for 5 hours; both of these regimens were administered during a 10-week period) with that of a time-matched exercise program for the more affected arm or a no-treatment control regimen. Subjects Thirty-five subjects with chronic stroke participated in the study.MethodsThe Action Research Arm Test (ARAT), Fugl-Meyer Assessment of Motor Recovery After Stroke (FM), and Motor Activity Log (MAL) were administered to the subjects.ResultsAfter intervention, significant differences were observed on the ARAT and MAL Amount of Use and Quality of Movement scales, all in favor of the mCIT group.Discussion and ConclusionThe data affirm previous findings suggesting that this reimbursable, outpatient protocol increases more affected arm use and function. Magnitude of changes was consistent with those reported in more intense protocols, such as constraint-induced therapy.