INCIDENCE AND ANATOMIC DISTRIBUTION OF CUTANEOUS MELANOMA AMONG UNITED-STATES HISPANICS
INCIDENCE AND ANATOMIC DISTRIBUTION OF CUTANEOUS MELANOMA AMONG UNITED-STATES HISPANICS
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DOI：
10.1002/jso.2930400404
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发表时间：
1989-04-01
影响因子：
2.5
通讯作者：
KRIPKE, ML
中科院分区：
文献类型：
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作者：
BERGFELT, L;NEWELL, GR;KRIPKE, ML
利用国家癌症研究所监测、流行病学和最终结果（SEER）项目编制的黑色素瘤发病率数据库，我们比较了1973年至1981年西班牙裔和非西班牙裔高加索人群以及黑人原发性皮肤黑色素瘤的发病率和解剖分布。病例分为美国白人、新墨西哥州（NM）白人（非西班牙裔高加索人）、NM西班牙裔、根据定义为西班牙裔的波多黎各（PR）居民和美国黑人。在白人中，发病率最高为每10万人8.0人，是美国黑人的10倍。PR和NM西班牙裔居民的发病率是美国黑人的1.6至3.7倍。两种性别的NM西班牙裔人的解剖分布与美国和NM白人相似。相反，在PR居民中，男性和女性的腿部解剖分布最常见，与黑人相似。移民到PR的西班牙人比移民到大陆的西班牙人有更多的非洲黑人。这表明PR居民下肢黑色素瘤发生的遗传偏好，而不是NM西班牙裔。
Using the data base for melanoma incidence compiled by the Surveillance, Epidemilogy, and End Results (SEER) Program of the National Cancer Institute, we compared the incidence and anatomic distribution of primary cutaneous melanomas in Hispanic and non-Hispanic Caucasian populations and in blacks between 1973 and 1981. Cases were divided into United States whites, New Mexico (NM) whites (non-Hispanic Caucasians), NM Hispanics, Puerto Rico (PR) residents by definition Hispanic, and US blacks. Among whites, the highest incidence was 8.0 per 100,000 and was ten times that of US blacks. The incidence among PR and NM Hispanic residents was 1.6 to 3.7 times that of US blacks. The anatomic distribution among NM Hispanics was similar to US and NM whites for both genders. In contrast, among PR residents the anatomic distribution in both genders was most common for the leg, similar to that for blacks. Spaniards who migrated to PR have more admixture with blacks from Africa than Spaniards who migrated to the mainland. This suggests a genetic predilection for the occurence of melanoma on the lower extremity among PR residents as opposed to NM Hispanics.