A left amygdala mediated network for rapid orienting to masked fearful faces
A left amygdala mediated network for rapid orienting to masked fearful faces
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DOI：
10.1016/j.neuropsychologia.2009.01.026
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发表时间：
2009-04-01
期刊：
影响因子：
2.6
通讯作者：
Habib, Reza
中科院分区：
文献类型：
--
作者：
Carlson, Joshua M.;Reinke, Karen S.;Habib, Reza
对环境威胁的快速反应是高度适应性的，恐惧的面部表情是重要的威胁线索。这些威胁线索的生物学意义是通过杏仁核对向后隐藏的恐惧面孔的反应的神经影像学研究结果来证明的。此外，行为点探针研究表明，向后掩盖恐惧的面孔调节空间注意力。然而，人们对杏仁核对被掩盖的恐惧面孔的敏感性的行为影响知之甚少。使用点探测任务与事件相关的功能磁共振成像（fMRI），我们提供的第一个证据表明，杏仁核是参与定向到后面掩盖可怕的面孔。此外，这种空间注意相关杏仁核反应与前扣带回、上级颞沟和舌回的活动相关。出版社：Elsevier Ltd
A rapid response to environmental threat is highly adaptive and fearful facial expressions serve as important threat cues. The biological significance of these threat cues is demonstrated by neuroimaging findings of amygdala responses to backward masked fearful faces. Additionally, behavioral dot-probe studies reveal that backward masked fearful faces modulate spatial attention. However, little is known about the behavioral impact of the amygdala sensitivity to masked fearful faces. Using a dot-probe task with event-related functional magnetic resonance imaging (fMRI), we provide the first evidence that the amygdala is involved in orienting to backward masked fearful faces. Furthermore, this spatial attention-related amygdala response was correlated with activity in the anterior cingulate, superior temporal sulcus, and lingual gyrus. Published by Elsevier Ltd.