[The OCCGE (Organisation de Coordination et de Coopération pour la Lutte contre les Grandes Endémies) and the surveillance of the drug sensitivity of Plasmodium falciparum to antimalarials].
[The OCCGE (Organisation de Coordination et de Coopération pour la Lutte contre les Grandes Endémies) and the surveillance of the drug sensitivity of Plasmodium falciparum to antimalarials].
复制标题
[OCCGE（Organization de Coordination et de Coopération pour la Lutte contre les Grandes Endémies）和恶性疟原虫对抗疟药药物敏感性的监测]。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
J. Breman
中科院分区：
文献类型：
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作者：
A. Gbary;T. R. Guiguemdé;J. Ouédraogo;D. Baudon;C. Douchet;J. Le Bras;J. Breman
抗药性从东非向中非蔓延是西非一个非常令人担忧的问题。事实上，目前在初级卫生保健框架内，对发热发作进行化疗被视为疟疾控制战略。这一新的战略是基于这样一个事实，即常用的抗疟疾药物，如氯喹，肯定是有效的。因此，监测恶性疟原虫地方株的化学敏感性成为优先事项。根据多年来在布基纳法索进行的研究，O.C.C.G.E.组织了一个分几个层次的监测系统：一个参考中心、每个国家的一个国家中心和设在各国不同流行病学特征地区的监测中心。这种对许多国家的监测可以更快地发现与耐药性有关的一些可能的问题，并采取措施限制其影响。
Spreading of chemoresistance from East Africa to Central Africa is a very worrying problem for Western Africa. In fact, chemotherapy of febrile attacks is at present admitted as malaria control strategy in the framework of Primary Health Care. This new strategy is based on the fact that commonly used antimalarial drugs as chloroquine are surely efficacious. Thus, the surveillance of chemosensitivity of Plasmodium falciparum local strains becomes a priority. From studies carried out in Burkina Faso during many years, Centre Muraz of O.C.C.G.E. has organized a surveillance system with several levels: a Reference Center, a National Center for each country and sentinel centers located in the different epidemiological features of the countries. This surveillance concerning many states can allow to detect more quickly some possible problems in relation with chemoresistance and to take measures to limit its impact.