Using Phase Data From MR Temperature Imaging to Visualize Anatomy During MRI-Guided Focused Ultrasound Neurosurgery.
Using Phase Data From MR Temperature Imaging to Visualize Anatomy During MRI-Guided Focused Ultrasound Neurosurgery.
复制标题
DOI：
10.1109/tmi.2020.3005631
复制
发表时间：
2020-12
影响因子：
10.6
通讯作者：
Rees Cosgrove G
中科院分区：
文献类型：
--
作者：
McDannold N;Jason White P;Rees Cosgrove G
由于图像质量差，在经颅mri引导的聚焦超声（MRgFUS）热消融过程中，识别丘脑中的神经外科目标具有挑战性。它们也邻近的结构，如果受损可能会导致副作用。在这里，我们证明在MRgFUS期间获得的相位数据用于MR温度成像（MRTI）包含解剖信息，可以用于指导该程序。该方法在68例特发性震颤（ET）的丘脑切除术中进行了评估。我们发现我们可以很容易地看到红色核和丘脑下核，这些核始终与超声目标坐标对齐。我们还可以持续地观察内部胶囊，它需要被保护起来，防止热损伤，以防止副作用。帕金森氏病患者的4例苍白球切开术的初步结果表明，这种方法除了可以观察内囊外，还可以观察视神经束。总的来说，这种方法可以可视化解剖标志，这可能有助于改进基于图谱的MRgFUS靶向。由于MRTI和解剖可视化使用了相同的数据，因此不会因对先前获得的规划图像进行配准而产生误差或图像失真，也不需要额外的时间。
Neurosurgery targets in the thalamus can be challenging to identify during transcranial MRI-guided focused ultrasound (MRgFUS) thermal ablation due to poor image quality. They also neighbor structures that can result in side effects if damaged. Here we demonstrate that the phase data obtained during MRgFUS for MR temperature imaging (MRTI) contains anatomic information that could be useful in guiding this procedure. This approach was evaluated in 68 thalamotomies for essential tremor (ET). We found that we could readily visualize the red nucleus and subthalamic nucleus, and those nuclei were consistently aligned with the sonication target coordinates. We also could consistently visualize the internal capsule, which needs to be protected from thermal damage to prevent side effects. Preliminary results from four pallidotomies in Parkinson’s disease patients suggest that this approach might also be useful in visualizing the optic tract in addition to the internal capsule. Overall, this approach can visualize anatomic landmarks that may be useful to refine atlas-based targeting for MRgFUS. Since the same data is used for MRTI and anatomic visualization, there are no errors induced by registration to previously obtained planning images or image distortion, and no additional time is needed.