Succinimide-Promoted Malonylamination of Alkenes with Amines and Iodonium Ylides via Trapping of Transient Aminium Radical Cations
Succinimide-Promoted Malonylamination of Alkenes with Amines and Iodonium Ylides via Trapping of Transient Aminium Radical Cations
复制标题
琥珀酰亚胺促进烯烃与胺和碘鎓叶立德通过捕获瞬态铵自由基阳离子进行丙二酰胺化
DOI：
10.1021/acs.orglett.9b00983
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发表时间：
2019
期刊：
影响因子：
5.2
通讯作者：
Wang Yao
中科院分区：
文献类型：
--
作者：
Zhang Liang;Kong Xiangjin;Liu Shuya;Zhao Zhiguo;Yu Qun;Wang Wei;Wang Yao
A conceptually distinct strategy enabling malonylamination of alkenes with abundant amines and iodonium ylides without assistance of any transition metal was developed. Succinimide was identified as a proton shuttle that can not only largely accelerate the process of trapping highly unstable radical ion pairs with alkenes but also significantly improve the chemical yields.
