Studies directed towards the total synthesis of clavosolides: synthesis of an isomer of clavosolide A
Studies directed towards the total synthesis of clavosolides: synthesis of an isomer of clavosolide A
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DOI：
10.1016/j.tetlet.2006.01.130
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发表时间：
2006-03-27
影响因子：
1.8
通讯作者：
Reddy, VR
中科院分区：
文献类型：
--
作者：
Chakraborty, TK;Reddy, VR
Clavosolide A 的全合成，采用自由基介导的途径构建其取代的四氢吡喃单元，山口反应构建二内酯苷元，最后的糖苷化步骤采用 Schmidt 方法，表明所报道的结构是天然产物的异构体。 (c) 2006 Elsevier Ltd. 保留所有权利。
The total synthesis of clavosolide A, employing a radical-mediated route to build its substituted tetrahydropyran unit, a Yamaguchi reaction to construct the diolide aglycon and the Schmidt method for the final glycosidation step, revealed that the reported structure is an isomer of the natural product. (c) 2006 Elsevier Ltd. All rights reserved.