Changing epidemiology of pertussis in the United States:: Increasing reported incidence among adolescents and adults, 1990-1996
Changing epidemiology of pertussis in the United States:: Increasing reported incidence among adolescents and adults, 1990-1996
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DOI：
10.1086/514776
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发表时间：
1999-06-01
影响因子：
11.8
通讯作者：
Livengood, JR
中科院分区：
文献类型：
--
作者：
G端ris, D;Strebel, PM;Livengood, JR
自 1990 年以来，美国报告的百日咳发病率有所增加，每 3-4 年出现一次高峰。根据疾病预防控制中心报告的百日咳病例分析，5岁以下儿童的发病率保持稳定，其中大多数都受到疫苗接种的保护。与1990-1993年相比，1994-1996年间，5-9岁、10-19岁和20岁以上人群的平均发病率分别增加了40%、106%和93%。自 1990 年以来，有 14 个州报告在 1990 年至 1996 年至少 4 年期间，百日咳发病率大于或等于每 10 万人口 2 例；其中七个国家还报告说，很大一部分病例发生在 10 岁或以上的人身上。对国家百日咳数据的分析没有提供足够的信息来充分阐明青少年和成人百日咳发病率增加的多种可能解释的相对重要性。这个年龄段的百日咳诊断和报告的改进，特别是在一些州，是导致总体增长的一个重要因素。
Since 1990, the reported incidence of pertussis has increased in the United States with peaks occurring every 3-4 years. On the basis of analysis of pertussis cases reported to the Centers for Disease Control and Prevention, the incidence remained stable among children aged younger than 5 years, most of whom were protected by vaccination. In contrast to 1990-1993, during 1994-1996, the average incidence among persons aged 5-9 years, 10-19 years, and 20 years or older increased 40%, 106%, and 93%, respectively. Since 1990, 14 states reported pertussis incidences of greater than or equal to 2 cases per 100,000 population during at least 4 years between 1990 and 1996; seven of these states also reported that a high proportion of cases occurred in persons aged 10 years or older. Analysis of national data on pertussis did not provide sufficient information to fully elucidate the relative importance of multiple possible explanations for the increase in the incidence of pertussis in adolescents and adults. Improvement in diagnosis and reporting of pertussis in this age group, particularly in some states, is an important factor contributing to the overall increase.