Lateral trapping of DNA inside a voltage gated nanopore.
Lateral trapping of DNA inside a voltage gated nanopore.
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电压门控纳米孔内 DNA 的横向捕获
DOI：
10.1103/physreve.95.062413
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
P. Reimann
中科院分区：
文献类型：
--
作者：
T. Töws;P. Reimann
当穿孔膜包含嵌入电极时，通过纳米孔处理短DNA片段的易位。精确的数值解的耦合泊松，能，普朗克，和斯托克斯方程的现实，全三维设置以及解析近似的简化模型工作。通过对膜电极施加合适的电压，可以强制DNA沿着孔轴或在距离孔壁很小但有限的距离上优选地穿过孔。
The translocation of a short DNA fragment through a nanopore is addressed when the perforated membrane contains an embedded electrode. Accurate numerical solutions of the coupled Poisson, Nernst-Planck, and Stokes equations for a realistic, fully three-dimensional setup as well as analytical approximations for a simplified model are worked out. By applying a suitable voltage to the membrane electrode, the DNA can be forced to preferably traverse the pore either along the pore axis or at a small but finite distance from the pore wall.