Effects of exercise training on arterial stiffness in older hypertensive females
Effects of exercise training on arterial stiffness in older hypertensive females
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DOI：
10.1007/s00421-015-3168-y
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发表时间：
2015-09-01
影响因子：
3
通讯作者：
Sugino, Megumi
中科院分区：
文献类型：
--
作者：
Miura, Hajime;Takahashi, Yoshinori;Sugino, Megumi
建议定期进行体育锻炼，以预防和治疗心血管疾病。然而，目前尚不清楚运动训练对老年高血压患者动脉僵硬度的影响是否与老年健康受试者相同。本研究的目的是比较运动训练对老年高血压和健康女性动脉硬化的影响，92名未经治疗的高血压女性和108名健康女性被随机分配到对照组或参加12周的训练计划。训练组每周2次，每次90 min，连续训练12周。每个训练计划包括娱乐活动，六到八个阻力练习电路训练和椅子上的下肢运动。采用自动脉搏波形分析仪测定仰卧位收缩压/舒张压（SBP/DBP）和臂踝脉搏波传导速度（baPWV），与对照组比较，两组baPWV和SBP/DBP均明显降低（P < 0.05）。此外，委员会认为，高血压组和对照组训练前后baPWV差值有显著性差异，（-72.5 +/- A 8.1 cm s（-1））和健康女性（-131.5 +/- A 107.3 cm s（-1））参加培训计划的这些数据表明，运动训练对老年高血压女性动脉硬化的改善程度低于老年健康女性。
Regular physical exercise is recommended for the prevention and treatment of cardiovascular disease. However, it is unclear whether the effects of exercise training on arterial stiffness are the same in older hypertensive individuals as those observed in older healthy subjects. The aim of this study was to compare the effects of exercise training on arterial stiffness between older hypertensive and healthy females.Ninety-two females with untreated hypertension and 108 healthy females were randomly assigned to either the control group or to participate in a 12-week training program. In the training groups, the subjects engaged in 90 min of training twice a week for 12 weeks. Each training program included recreational activities, six to eight resistance exercises for circuit training and chair-based exercise for the lower extremities. The systolic/diastolic blood pressure (SBP/DBP) and brachial to ankle pulse wave velocity (baPWV) were obtained in the supine position using an automatic pulse wave form analyzer.Compared with that observed in the control group, greater reductions in the baPWV and SBP/DBP were achieved in both training groups (P < 0.05). Furthermore, a significant difference in the delta baPWV values obtained before and after training was noted between the hypertensive (-72.5 +/- A 8.1 cm s(-1)) and healthy females (-131.5 +/- A 107.3 cm s(-1)) who participated in the training program (P < 0.05).These data indicate that exercise training produces fewer improvements in arterial stiffness in older hypertensive females than in older healthy females.