A case-control study of obstetric complications and later autistic disorder
A case-control study of obstetric complications and later autistic disorder
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DOI：
10.1007/bf02172829
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发表时间：
1996-08-01
影响因子：
3.9
通讯作者：
OCallaghan, E
中科院分区：
文献类型：
--
作者：
Cryan, E;Byrne, M;OCallaghan, E
自闭症的确切病因尚不清楚。产科逆境已被描述为可能增加患病风险的一个因素。我们在都柏林的四家妇产医院检查了49名符合DSM-III-R自闭症标准的儿童的同期出生记录，并使用该医院以前的同缝活产作为对照。使用两种产科并发症（OC）评定量表对数据进行盲评估。在产科逆境指数组和对照组之间没有发现显著差异。孤独症患者与对照组在先前描述的孤独症风险因素（产妇年龄、产妇胎次、出生顺序和低出生体重）方面没有区别。这些数据并不支持强迫症会增加日后患自闭症风险的观点。
The precise etiology of autism remains unclear. Obstetric adversity has been described as one factor that may increase the risk for the disorder. We examined the contemporaneous birth records of 49 children satisfying DSM-III-R criteria for autistic disorder, at four Dublin maternity hospitals, using the previous same-sew live birth in that hospital as a control. Data were evaluated blind to subject status using two obstetric complication (OC) rating scales. No significant differences in obstetric adversity were found between index and control groups. Autistic individuals did not differ from controls in terms of previously described risk factors for this disorder (maternal age, maternal parity, birth order, and low birth weight) in autism. These data do not support the view that OCs increase the risk for later autism.