Natively fat-suppressed 5D whole-heart MRI with a radial free-running fast-interrupted steady-state (FISS) sequence at 1.5T and 3T

Natively fat-suppressed 5D whole-heart MRI with a radial free-running fast-interrupted steady-state (FISS) sequence at 1.5T and 3T
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DOI:
10.1002/mrm.27942
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发表时间:
2019-08-27
影响因子:
3.3
通讯作者:
Stuber, Matthias
Stuber, Matthias
中科院分区:
医学3区
文献类型:
--
作者:
Bastiaansen, Jessica A. M.;Piccini, Davide;Stuber, Matthias

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目的 实施、优化和测试 1.5 特斯拉 (T) 和 3T 下本机脂肪抑制自由运行 5D 全心 MRI 的快速中断稳态 (FISS)。方法 FISS 用于在 1.5T 和 3T 下对心脏进行完全自门控自由运行心脏和呼吸运动分辨径向成像。进行数值模拟和体模扫描来比较脂肪抑制特性并确定有效脂肪抑制的参数范围(每个 FISS 模块和 TR 的读数 [NR] 数量)。随后,收集了 10 名健康志愿者的自由运行 FISS 数据,并使用压缩感知重建图像。将所有采集数据与相同序列的连续平衡稳态自由进动版本进行比较,并分析脂肪抑制和扫描时间。结果模拟表明 FISS 中抑制带的宽度和位置取决于 TR 和 NR。对于 100 Hz 和 NR 的脂肪抑制带宽
Purpose To implement, optimize, and test fast interrupted steady-state (FISS) for natively fat-suppressed free-running 5D whole-heart MRI at 1.5 tesla (T) and 3T. Methods FISS was implemented for fully self-gated free-running cardiac- and respiratory-motion-resolved radial imaging of the heart at 1.5T and 3T. Numerical simulations and phantom scans were performed to compare fat suppression characteristics and to determine parameter ranges (number of readouts [NR] per FISS module and TR) for effective fat suppression. Subsequently, free-running FISS data were collected in 10 healthy volunteers and images were reconstructed with compressed sensing. All acquisitions were compared with a continuous balanced steady-state free precession version of the same sequence, and both fat suppression and scan times were analyzed. Results Simulations demonstrate a variable width and location of suppression bands in FISS that were dependent on TR and NR. For a fat suppression bandwidth of 100 Hz and NR