DISSOCIATION OF OBJECT AND SPATIAL VISUAL PROCESSING PATHWAYS IN HUMAN EXTRASTRIATE CORTEX
DISSOCIATION OF OBJECT AND SPATIAL VISUAL PROCESSING PATHWAYS IN HUMAN EXTRASTRIATE CORTEX
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DOI：
10.1073/pnas.88.5.1621
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发表时间：
1991-03-01
影响因子：
11.1
通讯作者：
RAPOPORT, SI
中科院分区：
文献类型：
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作者：
HAXBY, JV;GRADY, CL;RAPOPORT, SI
对健康青年男性纹外物体识别和空间定位的独立视觉通路的存在和神经解剖位置进行了研究。通过正电子发射断层扫描和团注(H2O)-O-15测量局部脑血流量，同时受试者进行面部匹配、点位置匹配或感觉运动控制任务。这两项视觉匹配任务都激活了枕叶外侧皮质。面孔辨别单独激活了枕颞叶皮质的一个区域，该区域位于枕区的前面和下方，由两个任务激活。仅空间定位任务就激活了外上顶叶皮质的一个区域。任何一种任务都不能激活颞叶周围皮质和前额叶。这些结果证实了人眼视纹外皮层存在三个功能可分离的区域。分别负责物体识别和空间定位的区域的腹侧和背侧位置表明，人类和非人类灵长类动物纹外皮质之间存在某种同源性，并在人脑中发生移位，可能与系统发育较新的皮质区域的进化有关。
The existence and neuroanatomical locations of separate extrastriate visual pathways for object recognition and spatial localization were investigated in healthy young men. Regional cerebral blood flow was measured by positron emission tomography and bolus injections of (H2O)-O-15, while subjects performed face matching, dot-location matching, or sensorimotor control tasks. Both visual matching tasks activated lateral occipital cortex. Face discrimination alone activated a region of occipitotemporal cortex that was anterior and inferior to the occipital area activated by both tasks. The spatial location task alone activated a region of lateral superior parietal cortex. Perisylvian and anterior temporal cortices were not activated by either task. These results demonstrate the existence of three functionally dissociable regions of human visual extrastriate cortex. The ventral and dorsal locations of the regions specialized for object recognition and spatial localization, respectively, suggest some homology between human and nonhuman primate extrastriate cortex, with displacement in human brain, possibly related to the evolution of phylogenetically newer cortical areas.