Prediction of MEF2A-DNA interface by rigid body docking: A tool for fast estimation of protein mutational effects on DNA binding

Prediction of MEF2A-DNA interface by rigid body docking: A tool for fast estimation of protein mutational effects on DNA binding
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DOI:
10.1016/j.jsb.2005.12.002
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发表时间:
2006-03-01
影响因子:
3
通讯作者:
Ferrari, S
Ferrari, S
中科院分区:
生物学3区
文献类型:
--
作者:
Fanelli, F;Ferrari, S

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蛋白质-蛋白质对接算法ZDOCK首次在预测蛋白质- dna接触方面受到挑战。本研究中定义的计算方法已被证明在快速计算机估计MEF2A转录因子对DNA结合的突变效应方面是有效的。(C) 2005爱思唯尔公司版权所有。
The protein-protein docking algorithm ZDOCK has been challenged for the first time to predict protein-DNA contacts. The computational approach defined in this study has proven effectiveness in fast in silico estimations of mutational effects of the MEF2A transcription factor on DNA binding. (C) 2005 Elsevier Inc. All rights reserved.