EFFECTS OF CHRONIC COCAINE ABUSE ON MEMORY AND LEARNING
EFFECTS OF CHRONIC COCAINE ABUSE ON MEMORY AND LEARNING
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DOI：
10.1016/0887-6177(93)90048-6
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发表时间：
1993-11-01
影响因子：
2.6
通讯作者：
MOTTA, S
中科院分区：
文献类型：
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作者：
MITTENBERG, W;MOTTA, S
将16名每周至少戒酒10天（M = 20天）的慢性（M = 5年）可卡因使用者与年龄、教育程度、种族和性别匹配的对照进行加州语言学习测试，韦氏成人智力量表-修订（WAIS-R）词汇，排除有发育障碍的神经、精神或其他药物滥用史的块设计受试者。可卡因受试者学习和回忆的单词比对照组少，但在智商上没有差异。结果表明，长期使用可卡因后，语言学习效率的显著残余损害是由记忆储存困难引起的，而不是由注意力障碍或一般智力下降引起的。提出了一种剂量-反应关系。
Sixteen chronic (M = 5 years) weekly cocaine users who were at least 10 days (M = 20 days) abstinent were compared to age, education, race, and gender matched controls on the California Verbal Learning Test, Wechsler Adult Intelligence Scale-Revised (WAIS-R) Vocabulary, and Block Design Subjects with developmental disorder neurological, psychiatric, or other substance abuse history were excluded. Cocaine subjects learned and recalled fewer words than controls, but did not differ on IQ. Results suggested significant residual impairment in verbal learning efficiency subsequent to chronic cocaine use that results from memory storage difficulties rather than attentional impairment or general intellectual reduction. A dose-response relationship is suggested.