Twin-beams digital holography for 3D tracking and quantitative phase-contrast microscopy in microfluidics.
Twin-beams digital holography for 3D tracking and quantitative phase-contrast microscopy in microfluidics.
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DOI：
10.1364/oe.19.025833
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发表时间：
2011-12
期刊：
影响因子：
3.8
通讯作者：
P. Memmolo;A. Finizio;M. Paturzo;L. Miccio;P. Ferraro
中科院分区：
文献类型：
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作者：
P. Memmolo;A. Finizio;M. Paturzo;L. Miccio;P. Ferraro
我们报告了一种紧凑型双光束干涉仪，它可以作为具有双重功能的微流控平台的灵活诊断工具。这种新颖的结构允许对微小粒子进行3D跟踪，同时可以在不改变结构的情况下，通过干涉显微镜提供被跟踪微观对象的定量相位对比图。给出了微流控环境中体外细胞的实验演示。
We report on a compact twin-beam interferometer that can be adopted as a flexible diagnostic tool in microfluidic platforms with twofold functionality. The novel configuration allows 3D tracking of micro-particles and, at same time, can simultaneously furnish Quantitative Phase-contrast maps of tracked micro-objects by interference microscopy, without changing the configuration. Experimental demonstration is given on for in vitro cells in a microfluidic environment.